Metric reference¶
This table mirrors cofolder.modules.contracts.METRIC_CATALOG, the authoritative
registry used to validate public records. A metric appears only when its scope and
evidence are applicable. Direction describes optimization semantics, not a universal
scientific threshold.
| Metric | Group | Class | Type | Unit/scale | Direction | Scope | Evidence |
|---|---|---|---|---|---|---|---|
confidence_score |
confidence_metrics |
confidence | float | unitless | maximize | chain, system | reference_free |
ptm |
confidence_metrics |
confidence | float | unitless | maximize | chain, system | reference_free |
iptm |
confidence_metrics |
confidence | float | unitless | maximize | chain, system | reference_free |
chains_ptm |
confidence_metrics |
confidence | float | unitless | maximize | chain, system | reference_free |
chain_ptm |
confidence_metrics |
confidence | float | unitless | maximize | chain, system | reference_free |
sample_ranking_score |
confidence_metrics |
confidence | float | unitless | maximize | chain, system | reference_free |
avg_plddt |
confidence_metrics |
confidence | float | unitless | maximize | chain, system | reference_free |
ligand_iptm |
confidence_metrics |
confidence | float | unitless | maximize | system | reference_free |
protein_iptm |
confidence_metrics |
confidence | float | unitless | maximize | system | reference_free |
complex_plddt |
confidence_metrics |
confidence | float | unitless | maximize | system | reference_free |
complex_iplddt |
confidence_metrics |
confidence | float | unitless | maximize | system | reference_free |
complex_pde |
confidence_metrics |
confidence | float | unitless | minimize | system | reference_free |
complex_ipde |
confidence_metrics |
confidence | float | unitless | minimize | system | reference_free |
complex_pae |
confidence_metrics |
confidence | float | unitless | minimize | system | reference_free |
complex_ipae |
confidence_metrics |
confidence | float | unitless | minimize | system | reference_free |
gpde |
confidence_metrics |
confidence | float | unitless | minimize | chain, system | reference_free |
disorder |
confidence_metrics |
confidence | float | unitless | minimize | chain, system | reference_free |
has_clash |
confidence_metrics |
confidence | boolean | unitless | minimize | chain, system | reference_free |
pair_chains_iptm |
confidence_metrics |
confidence | float | unitless | maximize | chain_pair | reference_free |
chain_pair_iptm |
confidence_metrics |
confidence | float | unitless | maximize | chain_pair | reference_free |
bespoke_iptm |
confidence_metrics |
confidence | float | unitless | maximize | chain_pair | reference_free |
affinity_pred_value |
affinity_metrics |
affinity | float | log10(µM) | minimize | chain | reference_free |
affinity_probability_binary |
affinity_metrics |
binding | float | unitless | maximize | chain | reference_free |
pIC50 |
affinity_metrics_ext |
affinity | float | pIC50 | maximize | chain | reference_free |
IC50_M |
affinity_metrics_ext |
affinity | float | M | minimize | chain | reference_free |
IC50_uM |
affinity_metrics_ext |
affinity | float | µM | minimize | chain | reference_free |
pIC50_kcal_per_mol |
affinity_metrics_ext |
affinity | float | kcal/mol | maximize | chain | reference_free |
sasa |
structure_metrics |
structural | float | Ų | neutral | chain | reference_free |
sasa_norm_heavy |
structure_metrics |
structural | float | Ų/heavy atom | neutral | chain | reference_free |
ifp_distance |
structure_metrics |
structural | JSON | unitless | neutral | chain | reference_free |
ifp_distance_features |
structure_metrics |
structural | JSON | unitless | neutral | chain | reference_free |
ifp_prolif |
structure_metrics |
structural | JSON | unitless | neutral | chain | reference_free |
ifp_prolif_features |
structure_metrics |
structural | JSON | unitless | neutral | chain | reference_free |
ifp_prolif_events |
structure_metrics |
structural | string | unitless | neutral | chain | reference_free |
ligand_rmsd_ref |
reproduction_metrics |
reproduction | float | Å | minimize | chain, system | reference_structure |
protein_rmsd_ref |
reproduction_metrics |
reproduction | float | Å | minimize | chain, system | reference_structure |
ligand_rmsd_ref_mean |
reproduction_metrics |
reproduction | float | Å | minimize | chain, system | reference_structure |
protein_rmsd_ref_mean |
reproduction_metrics |
reproduction | float | Å | minimize | chain, system | reference_structure |
sucos_ref |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | reference_structure |
sucos_shape_ref |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | reference_structure |
sucos_feature_ref |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | reference_structure |
sucos_ref_mean |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | reference_structure |
ligand_pose_overlap_ref |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | reference_structure |
pocket_coverage_ref |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | reference_structure |
pocket_coverage_ref_mean |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | reference_structure |
pocket_coverage_custom |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | custom_pocket |
pocket_coverage_custom_mean |
reproduction_metrics |
reproduction | float | unitless | maximize | chain, system | custom_pocket |
bias_prot_sim_train |
bias_metrics |
training_proximity | float | percent identity | minimize | chain, system | reference_free |
bias_prot_sim_train_max |
bias_metrics |
training_proximity | float | percent identity | minimize | chain, system | reference_free |
bias_prot_sim_train_pairwise |
bias_metrics |
training_proximity | float | percent identity | minimize | chain, system | reference_free |
bias_prot_sim_train_pairwise_max |
bias_metrics |
training_proximity | float | percent identity | minimize | chain, system | reference_free |
bias_lig_sim_train |
bias_metrics |
training_proximity | float | Tanimoto | minimize | chain, system | reference_free |
bias_lig_sim_train_max |
bias_metrics |
training_proximity | float | Tanimoto | minimize | chain, system | reference_free |
ifp_filter_pass |
screen_metrics |
filter | boolean | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_overlap |
screen_metrics |
filter | float | unitless | maximize | compound | custom_pocket, reference_structure |
ifp_filter_similarity |
screen_metrics |
filter | float | unitless | maximize | compound | custom_pocket, reference_structure |
ifp_filter_threshold |
screen_metrics |
filter | float | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_status |
screen_metrics |
filter | string | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_reason |
screen_metrics |
filter | string | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_reference |
screen_metrics |
filter | string | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_similarity_metric |
screen_metrics |
filter | string | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_policy |
screen_metrics |
filter | string | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_taxonomy |
screen_metrics |
filter | string | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_mapping_status |
screen_metrics |
filter | string | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_required_interactions |
screen_metrics |
filter | JSON | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_missing_interactions |
screen_metrics |
filter | JSON | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_filter_mapping_failures |
screen_metrics |
filter | JSON | unitless | neutral | compound | custom_pocket, reference_structure |
ifp_cluster_id |
screen_metrics |
filter | string | unitless | neutral | compound | reference_free |
ifp_cluster_status |
screen_metrics |
filter | string | unitless | neutral | compound | reference_free |
oracle_score |
oracle_metrics |
oracle | float | unitless | neutral | compound | all regimes |
oracle_raw_score |
oracle_metrics |
oracle | float | unitless | neutral | compound | all regimes |
oracle_gate_adjusted_score |
oracle_metrics |
oracle | float | unitless | neutral | compound | all regimes |
struct_rmsd |
robustness_metrics |
robustness | float | Å | minimize | chain, system | reference_free |
Availability and missing values¶
Every metric record has one of computed, missing, unsupported, failed, or
not_requested. Only computed records contain a finite value; every other state
uses JSON null plus a machine-readable reason when applicable. Confidence,
binding likelihood, model-derived affinity, structural agreement, robustness, and
training proximity remain distinct diagnostic classes. A direction is not a claim
that one metric or threshold is universally valid.